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Original Article
The Effect of Testosterone on the Response of Grow Hormone Secretion in Cultured Rat Pituitary Cells
Ho Seong Kim, Duk Hi Kim, Deok Bae Park
Clin Exp Pediatr. 1993;36(11):1578-1582.   Published online November 15, 1993
The effects of testosterone on the pituitary growth hormone(GH) response directly and to hypothalamic growth hormone-releasing hormone(GHRH) were evaluated in vitro using a male pituitary cell monolayer culture system. Wistar male rats were gonadectomized at 22 days of age, and 21 days later their anterior pituitaries were removed and trypsinized for cell dispersion. Testosterone 0.01, 1.0, 10.0nM was added to...
The Effects of Testosterone on the Pituitary Growth Hormone Secretion
Ho Seong Kim, Duk Hi Kim, Kyung Za Ryu, Chang Mee Kim, Deok Bae Park
Clin Exp Pediatr. 1992;35(2):174-181.   Published online February 15, 1992
The effects of testosterone on growth hormone secretion and somatic growth have been reported in several previous studies. In order to investigate the role of testosterone in growth hormone secretion, we have studied the effect of testosterone on somatic growth, basal growth hormone concentration, and growth hormone response to growth hormone-releasing hormone (GHRH) in orchiectomized rats. In experiment 1, four groups...
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